General Information

  • ID:  hor003612
  • Uniprot ID:  P84663
  • Protein name:  Periviscerokinin-3
  • Gene name:  NA
  • Organism:  Derocalymma versicolor (Cockroach)
  • Family:  Periviscerokinin family
  • Source:  animal
  • Expression:  Expressed in abdominal perisympathetic organs and abdominal ganglia.
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Derocalymma (genus), Perisphaerinae (subfamily), Blaberidae (family), Blaberoidea (superfamily), Blattodea (order), Dictyoptera (superorder), Polyneoptera (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  GO:0005576 extracellular region

Sequence Information

  • Sequence:  GSSGMISFPRT
  • Length:  11
  • Propeptide:  GSSGMISFPRT
  • Signal peptide:  NA
  • Modification:  T11 Threonine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Myotropic activity
  • Mechanism:  NA
  • Cross BBB:  NO
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor003612_AF2.pdbhor003612_ESM.pdb

Physical Information

Mass: 131782 Formula: C48H78N14O16S
Absent amino acids: ACDEHKLNQVWY Common amino acids: S
pI: 10.55 Basic residues: 1
Polar residues: 6 Hydrophobic residues: 2
Hydrophobicity: -7.27 Boman Index: -1556
Half-Life: 30 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 35.45
Instability Index: 3725.45 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  19257902
  • Title:  A proteomic approach for studying insect phylogeny: CAPA peptides of ancient insect taxa (Dictyoptera, Blattoptera) as a test case.